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Abbreviations adme, absorption, distribution, metabolism, and excretion; hplc, high-performance liquid chromatography; fsa, flow scintillation analyzers; lc, liquid chromatography; arc, accurate radioisotope counting; ms, mass spectrometry; ms ms, tandem mass spectrometry; nmr, nuclear magnetic resonance; dmc, demethylcolchicine; gsh, glutathione; hresi, high-resolution electrospray ionization; psnr, peak signal noise ratio; roesy, rotating frame overhauser effect spectroscopy; hrms, high-resolution mass spectrometry.

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